APC Anti-Mouse FcεRIα Antibody
This is a APC Anti-Mouse FcεRIα Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.
Synonyms
High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, FcERI, Fcer1a
Gene ID
14125
Swiss Prot
P20489
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
APC
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
0.2 mg/mL
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Host or Source
Armenian Hamster
Isotype
Armenian Hamster IgG
Available Sizes
Curated Selection
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