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PE Anti-Mouse FcεRIα Antibody

This is a PE Anti-Mouse FcεRIα Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

Synonyms

High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, FcERI, Fcer1a

Gene ID

14125

Swiss Prot

P20489

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

PE

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

0.2 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Armenian Hamster

Isotype

Armenian Hamster IgG

Available Sizes

Curated Selection

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