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GNAT1 Polyclonal Antibody

This is a GNAT1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.GNAT1 (G Protein Subunit Alpha Transducin 1) is a Protein Coding gene. Diseases associated with GNAT1 include Night Blindness, Congenital Stationary, Autosomal Dominant 3 and Night Blindness, Congenital Stationary, Type 1G. Among its related pathways are Phospholipase-C Pathway and Phototransduction. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GNAT2.

Synonyms

CSNBAD3, GBT1, GNAT1, GNAT1, GNATR, guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1, guanine nucleotide binding protein G (T) alpha 1 subunit, Guanine nucleotide-binding protein G (t) subunit alpha-1, Rod specific transducin

Swiss Prot

P11488

Accession Number

NP000163

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human GNAT1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.66 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

40 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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