GP6 Polyclonal Antibody

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11) . Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Glycoprotein 6, Glycoprotein VI, GP6, GPIV, GPVI, GPVI, MGC138168, Platelet collagen receptor, Platelet glycoprotein VI, Platelet glycoprotein VI precursor