USP16 Polyclonal Antibody

This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Deubiquitinating enzyme 16, Human ubiquitin processing protease, MSTP039, Ubiquitin carboxyl-terminal hydrolase 16, Ubiquitin Specific peptidase 16, Ubiquitin Specific Protease 16, Ubiquitin thiolesterase 16, Ubiquitin-processing protease UBP-M, Ubiquitin-specifi