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ERCC1 Polyclonal Antibody

This is a ERCC1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5'-incision during DNA repair. It forms a complex with ERCC11, XPF and ERCC4, which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1, together with RRM1, are determinants of survival after surgical treatment of early-stage, non-small-cell lung cancer. (Ref: Simon, ER. 2005)

Synonyms

COFS 4, COFS4, DNA excision repair protein ERCC 1, DNA excision repair protein ERCC-1, DNA excision repair protein ERCC1, ERCC 1, ERCC1, ERCC1, Excision repair cross complementation group 1, Excision repair cross complementing 1, Excision Repair Cross Complementing

Swiss Prot

P07992

Accession Number

NP001974

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human ERCC1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1.1 mg/mL

Dilution

WB 1:500-1:2000, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

33 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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