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CBFA2T3 Polyclonal Antibody

This is a CBFA2T3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t (16;21) (q24; q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Synonyms

Cbfa2t3, Ccore binding factor runt domain alpha subunit 2 translocated to 3, ETO2, hMTG16, hMTG16a, hMTG16b, MTG16, MTG16, MTG8 related gene 2, MTG8 related protein MTG16a, MTG8 related protein MTG16b, MTG8-related protein 2, MTGR2, Myeloid translocation gene 8 and 16

Swiss Prot

O75081

Accession Number

NP005178

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human CBFA2T3

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1.1 mg/mL

Dilution

IHC 1:30-1:150, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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