IBA57 Polyclonal Antibody

The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.

C1orf69, CAF17, Chromosome 1 open reading frame 69, FLJ12734, FLJ13849, IBA57, IBA57 homolog iron sulfur cluster assembly, IBA57 iron sulfur cluster assembly homolog , IBA57 iron sulfur cluster assembly homolog (S. cerevisiae), IBA57, S. cerevisiae, homolog of, Iro