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GKN1 Polyclonal Antibody

This is a GKN1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Gastrokine 1 (GKN1), a stomach-specic protein also known as 18 kDa antrum mucosa protein (AMP-18) or foveolin, belongs to the gastrokine family of gastric mucus cell-secreted proteins. The human GKN1 gene has been localized in a region of chromosome 2p13 of about 6 kb and contains 6 exons. GKN1 is expressed only in normal human stomach, but is absent from gastric adenocarcinomas, gastro-esophageal adenocarcinoma cell lines, and other normal and tumor gastro-intestinal tissues. GKN1may play an important role in normal gastric function and may be a gastric tumour suppressor.

Synonyms

18 kDa antrum mucosa protein, AMP 18, AMP-18, AMP18, Antrum mucosa protein,18-KD, BRICD 1, BRICD1, BRICHOS domain containing 1, CA 11, CA11, CA11 gene, CA11 protein, FOV, Foveolin, Gastrokine-1, Gastrokine1, GKN 1, Gkn1, GKN1, MGC70354, Protein CA11, UNQ489/PRO1005

Swiss Prot

Q9NS71

Accession Number

NP062563

Reactivity

Human

Immunogen

Synthetic peptide of human GKN1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.5 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

22 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

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