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IBSP Polyclonal Antibody

This is a IBSP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Synonyms

BNSP, Bone sialoprotein 2, Bone sialoprotein II, BSP, BSP II, BSPII, Cell binding sialoprotein, Cell-binding sialoprotein, IBSP, Integrin binding sialoprotein, Integrin-binding sialoprotein, SIAL, SPII

Swiss Prot

P21815

Accession Number

NP004958

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human IBSP

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.84 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

35 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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