HIPK3 Polyclonal Antibody
This is a HIPK3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) .
Synonyms
Androgen receptor interacting nuclear protein kinase, Androgen receptor-interacting nuclear protein kinase, ANPK, DYRK6, Fas interacting serine/threonine protein kinase, Fas-interacting serine/threonine-protein kinase, FIST, FIST3, Hipk3, HIPK3, homeodomain interac
Swiss Prot
Q9H422
Accession Number
NP001041665
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human HIPK3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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