GATM Polyclonal Antibody

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders.

AGAT, AT, GATM, GATM, Glycine amidinotransferase, Glycine amidinotransferase, mitochondrial, L-arginine:glycine amidinotransferase, mitochondrial, Transamidinase