TCAP Polyclonal Antibody

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

19 kDa sarcomeric protein , CMD1N, CMH25, LGMD2G, Limb girdle muscular dystrophy 2G (autosomal recessive), T-cap, Tcap, TELE, Telethonin, TELT, Titin cap protein, Titin-cap