ITM2B Polyclonal Antibody
This is a ITM2B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
Synonyms
ABRI, ABri/ADan amyloid peptide, BRI 2, BRI, BRI2, BRICD 2B, BRICD2B, BRICHOS domain containing 2B, E25B, E3 16, E3-16, FBD, imBRI2, Immature BRI2, Integral membrane protein 2B, ITM 2B, ITM2B, ITM2B, Protein E25B, RDGCA, Transmembrane protein BRI
Swiss Prot
Q9Y287
Accession Number
BC000554
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human ITM2B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.2 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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