ATXN3 Polyclonal Antibody

Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG) n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

AT3, Ataxin 3, ataxin 3 variant h, ataxin 3 variant m, ataxin 3 variant ref, Ataxin-3, ATX3, ATX3, ATXN3, EC 3.4.22., JOS, Josephin, Machado Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3), Machado Joseph disease, Mac