VTI1A Polyclonal Antibody

The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs) . Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.

MMDS3, MVti1, SNARE Vti1a beta protein , Vesicle transport through interaction with t-SNAREs homolog 1A, Vesicle transport through interaction with tSNAREs homolog 1A (yeast), Vesicle transport v-SNARE protein Vti1-like 2, Vti1 rp2, Vti1-rp2, Vti1a, VTI1A vesicle