ZFAND5 Polyclonal Antibody
This is a ZFAND5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Synonyms
AN1-type zinc finger protein 5, ZA20D2, ZFAN5, Zfand5, ZFAND5A, zinc finger A20 domain containing 2 , Zinc finger A20 domain containing protein 2 , Zinc finger A20 domain-containing protein 2, zinc finger AN1 type domain 5, Zinc finger protein 216, ZNF216
Swiss Prot
O76080
Accession Number
BC011018
Reactivity
Human, Mouse, Rat
Immunogen
Full length fusion protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.4 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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