PE/Cyanine7 Anti-Human CD127/IL-7RA Antibody
This is a PE/Cyanine7 Anti-Human CD127/IL-7RA Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
Synonyms
Interleukin-7 receptor subunit alpha, IL-7RA, CDw127, CD127, IL-7Rα
Gene ID
3575
Swiss Prot
P16871
Reactivity
Human
Clonality
Monoclonal
Conjugation
PE/Cyanine7
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Host or Source
Mouse
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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