CEMIP Polyclonal Antibody
This is a CEMIP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
Synonyms
IR2155535, KIAA1199 protein, OTTHUMP00000185569 , OTTHUMP00000195036, TMEM2L, Transmembrane protein 2 like
Swiss Prot
Q8WUJ3
Accession Number
NP061159
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human CEMIP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.68 mg/mL
Dilution
IHC 1:100-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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