IL37 Polyclonal Antibody

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp) . This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. IL37 (Interleukin 37) is a Protein Coding gene. Diseases associated with IL37 include Rheumatoid Arthritis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.

FIL1, FIL1 zeta, FIL1 (ZETA), FIL1Z, IL 1 zeta, IL 1F7, IL 1F7b (IL 1H4, IL 1H, IL 1RP1), IL 1H4, IL 1RP1, IL 1X, IL 1X protein, IL-1 zeta, IL-1F7, IL-1H, IL-1H4, IL-1RP1, IL-1X, IL-37, IL1F7 (canonical product IL 1F7b), IL1F7, IL1F7, IL1H4, IL1RP1, Interleukin 1 family member 7, i