HNF4A Polyclonal Antibody

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

FLJ39654, FRTS4, Hepatic nuclear factor 4 alpha, Hepatocyte nuclear factor 4 alpha, Hepatocyte nuclear factor 4, Hepatocyte nuclear factor 4-alpha, HNF 4 alpha, HNF 4, HNF-4-alpha, HNF4, HNF4A, HNF4A, HNF4a7, HNF4a8, HNF4a9, Hnf4alpha, HNF4alpha10/11/12, MODY 1, MODY, MODY1