5,6-DM-cBIMP
5,6-DM-cBIMP, a cyclic nucleotide analog, is an agonist of PDE2 that can significantly enhance the cAMP and cGMP hydrolytic activities of PDE2[1][2.
Product Specifications
CAS Number
142754-31-2
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-6-dm-cbimp.html
Smiles
CC(C(C)=C1)=CC2=C1N(C=N2)[C@H]3[C@H](O)[C@H](OP4(O)=O)[C@@H](CO4)O3
Molecular Formula
C14H17N2O6P
Molecular Weight
340.27
References & Citations
[1]Nakashima K, et al. A Novel Inhibition Modality for Phosphodiesterase 2A[J]. SLAS DISCOVERY: Advancing the Science of Drug Discovery, 2020, 25 (5) : 498-505.|[2]Jäger R, et al. Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5[J]. British journal of pharmacology, 2010, 161 (7) : 1645-1660.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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