PROC Polyclonal Antibody

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]

Activation peptide, Anticoagulant protein C, APC, Autoprothrombin IIA, Blood coagulation factor XIV, EC 3.4.21.69, PC, proC, PROC, PROC1, Protein C (inactivator of coagulation factors Va and VIIIa), THPH3, THPH4, Vitamin K dependent protein C