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CDKL4 Polyclonal Antibody

This is a CDKL4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks) . Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.

Synonyms

CDKL4, CDKL4, Cyclin dependent kinase like 4, Cyclin-dependent kinase-like 4, EC 2.7.11.22, OTTHUMP00000164944

Swiss Prot

Q5MAI5

Accession Number

NP001009565

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human CDKL4

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.8 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

43 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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