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CAD Polyclonal Antibody

This is a CAD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

Aspartate carbamoyltransferase, Aspartate transcarbamylase, CAD protein, CAD trifunctional protein, Carbamoyl phosphate synthetase 2, Carbamoyl-phosphate synthetase 2 aspartate transcarbamylase and dihydroorotase, CPSase ATCase DHOase, Dihydroorotase, Glutamine d

Swiss Prot

P27708

Accession Number

NP004332

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human CAD

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.7 mg/mL

Dilution

IHC 1:40-1:200, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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