CYP11B2 Polyclonal Antibody
This is a CYP11B2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
Synonyms
ALDOS, Aldosterone synthase, Aldosterone-synthesizing enzyme, C11B2, CYP11B2, CYPXIB2, Cytochrome P-450Aldo, Cytochrome P-450C18, Cytochrome P450 11B2, Cytochrome P450 11B2, mitochondrial, mitochondrial, P-450Aldo, P-450C18, Steroid 18-hydroxylase
Swiss Prot
P19099
Accession Number
NP000489
Reactivity
Human
Immunogen
Synthetic peptide of human CYP11B2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Frequently Asked Questions
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