AF/LE Purified Anti-Mouse CD279/PD-1 Antibody
This is a AF/LE Purified Anti-Mouse CD279/PD-1 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2) . It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
Synonyms
PD-1, Programmed Death-1
Gene ID
18566
Swiss Prot
Q02242
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
None (Purified antibody-Azide Free/Low endotoxin)
Type
Flow Cytometry Antibody
Applications
FC, Block, Neut
Assay Type
Antibody
Concentration
0.5 mg/mL
Buffer
0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Storage Conditions
Store at 2~8°C. Do not freeze.
Host or Source
Rat
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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