LY593093

LY593093 is a selective, orally active, and brain-penetrant muscarinic M1 receptor agonist with an EC50 of 22.8 nM. LY593093 can be utilized in Alzheimer’s disease research[1].

Product Specifications

CAS Number

[1108748-12-4]

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly593093.html

Purity

98.82

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@@H]3C4=CC(/N=C(C)/N(C)CC5=CC=C(C=C5)F)=CC=C4C[C@H]3O

Molecular Formula

C32H30FN3O2

Molecular Weight

507.60

References & Citations

[1]Liu B, et al. Design and synthesis of N-[6- (Substituted Aminoethylideneamino) -2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M₁ agonists. Bioorg Med Chem Lett. 2015 Oct 1;25 (19) :4158-63.