Biotin Anti-Mouse CD49b Antibody
This is a Biotin Anti-Mouse CD49b Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection) . DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Synonyms
Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b
Gene ID
16398
Swiss Prot
Q62469
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
Biotin
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
0.5 mg/mL
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C. Do not freeze.
Host or Source
Rat
Isotype
Rat IgM, κ
Available Sizes
Curated Selection
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