AF/LE Purified Anti-Mouse CD119 Antibody
This is a AF/LE Purified Anti-Mouse CD119 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.
Synonyms
Interferon gamma receptor 1, Ifngr1, IFN-gamma-R1, IFN-gamma-R-alpha, CD119
Gene ID
15979
Swiss Prot
P15261
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
None (Purified antibody-Azide Free/Low endotoxin)
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
0.5 mg/mL
Buffer
0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Storage Conditions
Store at 2~8°C. Do not freeze.
Host or Source
Rat
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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