FBXW7 Polyclonal Antibody

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats.

AGO, Archipelago, Archipelago homolog, Archipelago, Drosophila, homolog of, CDC4, CDC4, S.cerevisiae, homolog of, DKFZp686F23254, F box and WD 40 domain protein 7 (archipelago homolog, Drosophila), F box and WD 40 domain protein 7, F box and WD repeat domain containing