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AF647 Anti-Mouse CD40 Antibody

This is a AF647 Anti-Mouse CD40 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Synonyms

Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5

Gene ID

21939

Swiss Prot

P27512

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

AF647

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Rat

Isotype

Rat IgG2a, κ

Available Sizes

Curated Selection

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