Purified Anti-Mouse CD40 Antibody
This is a Purified Anti-Mouse CD40 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Synonyms
Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5
Gene ID
21939
Swiss Prot
P27512
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
0.5 mg/mL
Buffer
PBS with 0.05% Proclin300
Storage Conditions
Store at 2~8°C. Do not freeze.
Host or Source
Rat
Isotype
Rat IgG2a, κ
Available Sizes
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