CBX-12
CBX-12 is an Exatecan-based peptide-drug conjugate (PDC) that utilizes a pH-sensitive pHLIP for antigen-independent tumor targeting and an auto-cleavable linker for payload release. It demonstrates antitumor activity in research models by inhibiting topoisomerase I (TOP1) in cancer cells, applicable for in vitro and in vivo oncology studies.
Product Specifications
Field of Research
Molecular Biology
Molecular Weight
3629.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog