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PGD97

PGD97 is a potent, selective cyclic peptide inhibitor of the CAL-CFTR interaction (KD = 6 nM) with >130-fold selectivity over NHERF1/2. It stabilizes F508del-CFTR at the plasma membrane, enhancing channel function in cystic fibrosis research models, applicable for in vitro and ex vivo mechanistic studies.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Molecular Weight

1643.01

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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