PGD97
PGD97 is a potent, selective cyclic peptide inhibitor of the CAL-CFTR interaction (KD = 6 nM) with >130-fold selectivity over NHERF1/2. It stabilizes F508del-CFTR at the plasma membrane, enhancing channel function in cystic fibrosis research models, applicable for in vitro and ex vivo mechanistic studies.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Molecular Weight
1643.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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