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IP3RCYT

IP3RCYT is a cell-permeable inhibitory peptide targeting the inositol 1,4,5-trisphosphate receptor (IP3R) with an IC50 of ~100 nM. It blocks cytochrome c binding to suppress pro-apoptotic calcium signaling, demonstrating anti-apoptotic effects in vitro in HeLa and Jurkat cells treated with staurosporine or FasL.

Product Specifications

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Molecular Weight

2073.2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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