OX40/TNFRSF4, Human (Biotinylated, HEK293, Fc-Avi)

OX40 (TNFRSF4), is a receptor for OX40 Ligand. OX40 is preferentially expressed by T cells. OX40 can be activated by OX40 Ligand, thereby functioning as a T cell co-stimulatory molecule. The OX40-OX40 Ligand interaction promotes effector T-cell survival and effectively induces memory T-cell generation, as well as enhances the helper function of Tfh for B cells, and also promotes the differentiation and maturation of DCs[1][2]. OX40/TNFRSF4 Protein, Human (Biotinylated, HEK293, Fc-Avi) is a recombinant biotinylated human OX40 (L29-A216) with C-terminal Avi and hFc tag, which is produced in HEK293.