Anti-Human CD68 Monoclonal Antibody, Flow Validated

Boster Bio Anti-Human CD68 Monoclonal Antibody Unconjugated Conjugated, Flow Validated (Catalog# FC00602) . Tested in Flow Cytometry application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Macrosialin; Gp110; CD68; CD68

Gene Name

CD68

UniProt

P34810

Host

Mouse

Reactivity

Human

Immunogen

Lysosomal fraction of human alveolar macrophages.

Clonality

Monoclonal

Clone

Clone: Clone: KP1

Tissue Specificity

Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.

Applications

Flow Cytometry

Field of Research

Cell Type Markers, Immunology

Purification

Affinity column chromatography

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

User needs to optimize the dilution ratio for this antibody.

Form

Liquid, in PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA

Function

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.