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Anti-KCNMB2 Antibody (N-term)

Boster Bio Anti-KCNMB2 Antibody (N-term) (Catalog # M08181) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.

Synonyms

Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, BKbeta2, Hbeta2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, Hbeta3, K (VCA) beta-2, Maxi K channel subunit beta-2, Slo-beta-2, KCNMB2

Gene Name

KCNMB2

UniProt

Q9Y691

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This KCNMB2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the N-terminal region of human KCNMB2.

Clonality

Polyclonal

Tissue Specificity

Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues

Applications

WB

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Dilution

WB: 1:2000

Function

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.

Molecular Weight

27130 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M08181

Product MSDS

https://www.bosterbio.com/msds?sku=M08181

Fragment

Rabbit IgG

Subcellular Location

Membrane; Multi-pass membrane protein.

Available Sizes

Curated Selection

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