Anti-ATG4A Antibody
Boster Bio Anti-ATG4A Antibody (Catalog # M06539-1) . Tested in WB, Flow Cytometry, IHC-P, IF application (s) . This antibody reacts with Human.
Product Specifications
Background
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Synonyms
Cysteine protease ATG4A, 3422-, AUT-like 2 cysteine endopeptidase, Autophagin-2, Autophagy-related cysteine endopeptidase 2, Autophagy-related protein 4 homolog A, hAPG4A, ATG4A, APG4A, AUTL2
Gene Name
ATG4A
UniProt
Q8WYN0
Host
Mouse
Reactivity
Human
Immunogen
This ATG4A antibody is generated from a mouse immunized with a recombinant protein.
Clonality
Monoclonal
Clone
Clone: 1458CT808.66.25.69
Applications
WB, Flow Cytometry, IHC-P, IF
Field of Research
Cancer, Cardiovascular, Cell Biology, Metabolism, Autophagy
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
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Molecular Weight
45378 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
IgG2b, k
Subcellular Location
Cytoplasm {ECO:0000250|UniProtKB:Q8BGE6}.
Available Sizes
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