What is the catalog number for Anti-LMCD1 Antibody (C-term)?

The catalog number for Anti-LMCD1 Antibody (C-term) is A08888.

Is Anti-LMCD1 Antibody (C-term) in stock?

Anti-LMCD1 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-LMCD1 Antibody (C-term)?

The safety data sheet for Anti-LMCD1 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A08888.

Anti-LMCD1 Antibody (C-term)

Boster Bio Anti-LMCD1 Antibody (C-term) (Catalog # A08888) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity) . Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

Synonyms

LIM and cysteine-rich domains protein 1, Dyxin, LMCD1

Gene Name

LMCD1

UniProt

Q9NZU5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.

Clonality

Polyclonal

Tissue Specificity

Expressed in the heart (at protein level) . Expressed in many tissues with highest abundance in skeletal muscle

Applications

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Dilution

WB: 1:1000

Function

Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6- mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity) . Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.