Anti-DEPDC1 Antibody (N-term)
Boster Bio Anti-DEPDC1 Antibody (N-term) (Catalog # A08594) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.
Product Specifications
Synonyms
DEP domain-containing protein 1A, DEPDC1, DEPDC1A
Gene Name
DEPDC1
UniProt
Q5TB30
Host
Rabbit
Reactivity
Human
Immunogen
This DEPDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 amino acids from the N-terminal region of human DEPDC1.
Clonality
Polyclonal
Tissue Specificity
Expressed in testis. Up-regulated in bladder cancer cells (at protein level) .
Applications
IHC-P, WB
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
Molecular Weight
92960 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
Nucleus. Note=Colocalizes with ZNF224 at the nucleus
Available Sizes
Frequently Asked Questions
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