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Anti-CREBL1 Antibody (C-term)

Boster Bio Anti-CREBL1 Antibody (C-term) (Catalog # A08395-1) . Tested in IHC-P, WB application (s) . This antibody reacts with Human, Hamster, Mouse.

Product Specifications

Background

CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.

Synonyms

Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein, Creb-rp, cAMP-responsive element-binding protein-like 1, Processed cyclic AMP-dependent transcription factor ATF-6 beta, ATF6B, CREBL1, G13

Gene Name

ATF6B

UniProt

Q99941

Host

Rabbit

Reactivity

Human, Hamster, Mouse

Immunogen

This CREBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

IHC-P, WB

Field of Research

Apoptosis

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

1125694411256944

Molecular Weight

76709 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A08395-1

Product MSDS

https://www.bosterbio.com/msds?sku=A08395-1

Fragment

Rabbit IgG

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type II membrane protein

Available Sizes

Curated Selection

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