Anti-APEX2 Antibody (Center)
Boster Bio Anti-APEX2 Antibody (Center) (Catalog # A07203-2) . Tested in WB, IF, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.
Product Specifications
Background
APEX2 may participate in both nuclear and mitochondrial post-replicative base excision repair (BER) . In the nucleus functions in the PCNA-dependent BER pathway.
Synonyms
DNA- (apurinic or apyrimidinic site) lyase 2, 31--, AP endonuclease XTH2, APEX nuclease 2, APEX nuclease-like 2, Apurinic-apyrimidinic endonuclease 2, AP endonuclease 2, APEX2, APE2, APEXL2, XTH2
Gene Name
APEX2
UniProt
Q9UBZ4
Host
Rabbit
Reactivity
Human
Immunogen
This APEX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-171 amino acids from the Central region of human APEX2.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in brain and kidney. Weakly expressed in the fetal brain.
Applications
WB, IF, Flow Cytometry, IHC-P
Field of Research
Mitochondria
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
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Molecular Weight
57401 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00764, ECO:0000269|PubMed:11376153, ECO:0000269|PubMed:19443450}. Cytoplasm Mitochondrion. Note=Together with PCNA, is redistributed in discrete nuclear foci in presence of oxidative DNA damaging agents.
Available Sizes
Frequently Asked Questions
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