Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TBX6 Antibody (Center W158)

Selected Variant

A05398-1-01

Size: 80 µL

Boster Bio Anti-TBX6 Antibody (Center W158) (Catalog # A05398-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures.

Synonyms

T-box transcription factor TBX6, T-box protein 6, TBX6

Gene Name

TBX6

UniProt

O95947

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TBX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of human TBX6.

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus

Applications

WB, Flow Cytometry

Field of Research

Developmental Biology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity) .

Molecular Weight

47045 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

Rabbit IgG

Subcellular Location

Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.

Prediction Reactivity

Bovine, Rat

Available Sizes

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-IAH1 Antibody Picoband®, Carrier-free
A14534-1-carrier-free 100 µg/Vial

Anti-IAH1 Antibody Picoband®, Carrier-free

Sign In for Pricing
View Details
CD66, pan (CEA) (Cocktail), 0.2mg/mL
BNUB1139-500 1x 500 µL

CD66, pan (CEA) (Cocktail), 0.2mg/mL

Sign In for Pricing
View Details