What is the catalog number for Anti-ATAD2 Antibody (N-term)?

The catalog number for Anti-ATAD2 Antibody (N-term) is A03855.

Is Anti-ATAD2 Antibody (N-term) in stock?

Anti-ATAD2 Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-ATAD2 Antibody (N-term)?

The safety data sheet for Anti-ATAD2 Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A03855.

Anti-ATAD2 Antibody (N-term)

Boster Bio Anti-ATAD2 Antibody (N-term) (Catalog # A03855) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. The proteins that belong to this family either contain one or two AAA (ATPases Associated with diverse cellular Activities) domains. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. The protein encoded by this gene contains two AAA domains, as well as a bromodomain.

Synonyms

ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ANCCA, ATAD2

Gene Name

ATAD2

UniProt

Q6PL18

Host

Rabbit

Reactivity

Human

Immunogen

This ATAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the N-terminal region of human ATAD2.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.

Applications

Field of Research

Cancer, Metabolism, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Dilution

WB: 1:1000

Function

May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.