Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-SERPINA3 Antibody (C-term)

Boster Bio Anti-SERPINA3 Antibody (C-term) (Catalog # A02312-2) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Synonyms

Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, SERPINA3, AACT

Gene Name

SERPINA3

UniProt

P01011

Host

Rabbit

Reactivity

Human

Immunogen

This SERPINA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the C-terminal region of human SERPINA3.

Clonality

Polyclonal

Tissue Specificity

Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.

Applications

Flow Cytometry, WB

Field of Research

Cardiovascular, Cell Biology, Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

Molecular Weight

47651 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02312-2

Product MSDS

https://www.bosterbio.com/msds?sku=A02312-2

Fragment

Rabbit IgG

Subcellular Location

Secreted.

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

OR5AK4P AAV Vector (Human) (CMV)
35382101 1 μg

OR5AK4P AAV Vector (Human) (CMV)

Ask
View Details
CXorf58 Human shRNA Plasmid Kit (Locus ID 254158)
TR307652 1 Kit

CXorf58 Human shRNA Plasmid Kit (Locus ID 254158)

Ask
View Details
TRNAQ23 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
48293111 3 x 1.0 µg

TRNAQ23 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

Ask
View Details
Anti-CD62L (L-Selectin)(LAM1-116), CF740 conjugate
BNC741587-500 500 µL

Anti-CD62L (L-Selectin)(LAM1-116), CF740 conjugate

Ask
View Details
Peripherin (PRPH) Mouse Monoclonal Antibody [Clone:8G3]
E45M17257 100 ug

Peripherin (PRPH) Mouse Monoclonal Antibody [Clone:8G3]

Ask
View Details