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Anti-HUMAN-SHB (Y268) Antibody

Boster Bio Anti-HUMAN-SHB (Y268) Antibody (Catalog # A02109-1) . Tested in IHC-P, Flow Cytometry, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.

Synonyms

SH2 domain-containing adapter protein B, SHB

Gene Name

SHB

UniProt

Q15464

Host

Rabbit

Reactivity

Human

Immunogen

This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 250-290 amino acids from human.

Clonality

Polyclonal

Tissue Specificity

Widely expressed.

Applications

IHC-P, Flow Cytometry, WB

Field of Research

Developmental Biology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin- producing cells.

Molecular Weight

55042 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

Rabbit IgG

Subcellular Location

Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associates with membrane lipid rafts upon TCR stimulation

Available Sizes

Frequently Asked Questions

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