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Anti-MyoD1 Antibody (Center)

Boster Bio Anti-MyoD1 Antibody (Center) (Catalog # A00964-1) . Tested in IF, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.

Synonyms

Myoblast determination protein 1, Class C basic helix-loop-helix protein 1, bHLHc1, Myogenic factor 3, Myf-3, MYOD1, BHLHC1, MYF3, MYOD

Gene Name

MYOD1

UniProt

P15172

Host

Rabbit

Reactivity

Human

Immunogen

This MyoD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human MyoD1.

Clonality

Polyclonal

Applications

IF, WB

Field of Research

Developmental Biology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity) .

Molecular Weight

34501 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00964-1

Product MSDS

https://www.bosterbio.com/msds?sku=A00964-1

Fragment

Rabbit IgG

Subcellular Location

Nucleus.

Available Sizes

Curated Selection

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